[CH3:1][O:2][C:3](=[O:11])[CH2:4][C@H:5]([CH3:10])[CH2:6][C:7](O)=[O:8].[CH3:12][Si:13]([CH3:18])([CH3:17])[CH2:14][CH2:15][OH:16].C1CCC(N=C=NC2CCCCC2)CC1.C(=O)(O)[O-].[Na+]>C(Cl)Cl.CN(C1C=CN=CC=1)C>[CH3:12][Si:13]([CH3:18])([CH3:17])[CH2:14][CH2:15][O:16][C:7](=[O:8])[CH2:6][C@@H:5]([CH3:10])[CH2:4][C:3]([O:2][CH3:1])=[O:11]To the solution of 3-(R)-Methyl-pentanedioic acid monomethyl ester in methylene chloride was added 2-Trimethylsilanyl-ethanol followed by DCC and DMAP and was stirred for 30 minutes. The reaction mixture was treated with sodium bicarbonate and methylene chloride. The product was purified by column chromatography.
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