Chloride → N-[1-[4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-1-oxobutan-2-yl]cyclopentanecarboxamide

HRID 281466

Reaction equation

HRID 281466 reaction equation
[C:24](=[O:25])([Cl:26])[Cl:27].[CH2:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1.[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH:33]([N:34]([CH2:35][CH3:36])[CH:37]([CH3:38])[CH3:39])([CH3:40])[CH3:41].[Cl-:1].[Cl:2][c:3]1[cH:4][cH:5][c:6]([C:9]2([OH:23])[C:10]([CH3:21])([CH3:22])[CH2:11][N:12]([C:15]([CH:16]([CH2:17][CH3:18])[NH3+:19])=[O:20])[CH2:13][CH2:14]2)[cH:7][cH:8]1>>[Cl:2][c:3]1[cH:4][cH:5][c:6]([C:9]2([OH:23])[C:10]([CH3:21])([CH3:22])[CH2:11][N:12]([C:15]([CH:16]([CH2:17][CH3:18])[NH:19][C:24](=[O:25])[CH:28]3[CH2:29][CH2:30][CH2:31][CH2:32]3)=[O:20])[CH2:13][CH2:14]2)[cH:7][cH:8]1

Participants

7

Reactant 6

HCID 312ChlorideHCID 6371PhosgeneHCID 8028TetrahydrofuranHCID 9253CyclopentaneHCID 81531DiisopropylethylamineHCID 178458037[1-[4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-1-oxobutan-2-yl]azanium

Product 1

HCID 67299754N-[1-[4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-1-oxobutan-2-yl]cyclopentanecarboxamide

Sources & evidence

ORD record
ord-90c8d9586a62431e91a855e97e09e4a1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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