Chloride → 1-(4-Bromopyridin-2-yl)-4-methoxybutylamine

HRID 287151

Reaction equation

HRID 287151 reaction equation
[BH4-:17].[Br:1][c:2]1[cH:3][c:4]([C:8]#[N:9])[n:5][cH:6][cH:7]1.[CH3:11][O:12][CH2:13][CH2:14][CH2:15][Mg+:16].[CH3:26][CH2:27][O:28][C:29](=[O:30])[CH3:31].[CH3:32][OH:33].[Cl-:10].[Na+:18].[Na+:20].[O:21]1[CH2:22][CH2:23][CH2:24][CH2:25]1.[OH-:19]>>[Br:1][c:2]1[cH:3][c:4]([CH:8]([NH2:9])[CH2:15][CH2:14][CH2:13][O:12][CH3:11])[n:5][cH:6][cH:7]1

Participants

10

Reactant 9

HCID 312ChlorideHCID 887MethanolHCID 923Sodium ion2×HCID 961HydroxideHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 28123BorohydrideHCID 6932834-Bromo-2-cyanopyridineHCID 178495107HCID 178495107, compound

Product 1

HCID 686532511-(4-Bromopyridin-2-yl)-4-methoxybutylamine

Sources & evidence

ORD record
ord-b8106bc8dcae48d4862211fbac3c933d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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