Hydrochloric Acid → 5-bromo-3-(1-{[2-(methyloxy)ethyl]sulfonyl}-4-piperidinyl)-1H-indole-7-carboxamide

HRID 291017

Reaction equation

HRID 291017 reaction equation
[Br:10][c:11]1[cH:12][c:13]2[c:14]([CH:23]3[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]3)[cH:15][nH:16][c:17]2[c:18]([C:20](=[O:21])[NH2:22])[cH:19]1.[CH3:1][O:2][CH2:3][CH2:4][S:5](=[O:6])(=[O:7])[Cl:8].[CH3:30][N:31]([CH3:32])[CH:33]=[O:34].[CH3:35][CH2:36][N:37]([CH2:38][CH3:39])[CH2:40][CH3:41].[ClH:9].[OH2:29]>>[CH3:1][O:2][CH2:3][CH2:4][S:5](=[O:6])(=[O:7])[N:26]1[CH2:25][CH2:24][CH:23]([c:14]2[c:13]3[cH:12][c:11]([Br:10])[cH:19][c:18]([C:20](=[O:21])[NH2:22])[c:17]3[nH:16][cH:15]2)[CH2:28][CH2:27]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 962WaterHCID 6228DimethylformamideHCID 8471TriethylamineHCID 113247225-bromo-3-(4-piperidinyl)-1H-indole-7-carboxamideHCID 134802212-Methoxyethane-1-sulfonyl chloride

Product 1

HCID 596006625-bromo-3-(1-{[2-(methyloxy)ethyl]sulfonyl}-4-piperidinyl)-1H-indole-7-carboxamide

Sources & evidence

ORD record
ord-91ccae5b814042729ed8525257b7a303
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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