1,2-Dichloroethane → N-{2-[4-(Biphenyl-2-ylcarbamoyloxy)piperidin-1-yl]ethyl}-3-methoxy-N-methylterephthalamic Acid Methyl Ester

HRID 293959

Reaction equation

HRID 293959 reaction equation
[CH2:16]([Cl:17])[CH2:18][Cl:19].[CH3:1][O:2][C:3]([c:4]1[cH:5][c:6]([O:13][CH3:14])[c:7]([C:8](=[O:9])[OH:10])[cH:11][cH:12]1)=[O:15].[CH3:39][NH:40][CH2:41][CH2:42][N:43]1[CH2:44][CH2:45][CH:46]([O:49][C:50]([NH:51][c:52]2[c:53](-[c:58]3[cH:59][cH:60][cH:61][cH:62][cH:63]3)[cH:54][cH:55][cH:56][cH:57]2)=[O:64])[CH2:47][CH2:48]1.[CH:30]([N:31]([CH2:32][CH3:33])[CH:34]([CH3:35])[CH3:36])([CH3:37])[CH3:38].[O:65]=[CH:66][N:67]([CH3:68])[CH3:69].[OH:20][n:21]1[c:22]2[n:23][cH:24][cH:25][cH:26][c:27]2[n:28][n:29]1>>[CH3:1][O:2][C:3]([c:4]1[cH:5][c:6]([O:13][CH3:14])[c:7]([C:8](=[O:10])[N:40]([CH3:39])[CH2:41][CH2:42][N:43]2[CH2:44][CH2:45][CH:46]([O:49][C:50]([NH:51][c:52]3[c:53](-[c:58]4[cH:59][cH:60][cH:61][cH:62][cH:63]4)[cH:54][cH:55][cH:56][cH:57]3)=[O:64])[CH2:47][CH2:48]2)[cH:11][cH:12]1)=[O:15]

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 6228DimethylformamideHCID 81531DiisopropylethylamineHCID 181649HOAtHCID 566436031-(2-(Methylamino)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamateHCID 593403342-Methoxy-4-(methoxycarbonyl)benzoic acid

Product 1

HCID 59340332N-{2-[4-(Biphenyl-2-ylcarbamoyloxy)piperidin-1-yl]ethyl}-3-methoxy-N-methylterephthalamic Acid Methyl Ester

Sources & evidence

ORD record
ord-6c7a2c40a5f74dd2bc68df6fec247738
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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