Ammonia → 2-[1-(6-Tert-butoxycarbonylamino-pyridin-3-yl)-propyl]-malonic acid diethyl ester
Reaction equation
[Br-:1].[CH2:2]([CH3:3])[Mg+:4].[CH2:5]([CH3:6])[O:7][C:8]([C:9]([C:10](=[O:11])[O:12][CH2:13][CH3:14])=[CH:15][c:16]1[cH:17][n:18][c:19]([NH:22][C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[cH:20][cH:21]1)=[O:30].[CH3:33][CH2:34][O:35][CH2:36][CH3:37].[Cl-:31].[Cu:44]([I:45])[I:46].[NH3:43].[NH4+:32].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1>>[CH2:2]([CH3:3])[CH:15]([CH:9]([C:8]([O:7][CH2:5][CH3:6])=[O:30])[C:10](=[O:11])[O:12][CH2:13][CH3:14])[c:16]1[cH:17][n:18][c:19]([NH:22][C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[cH:20][cH:21]1
