Dimethylformamide → 3-(N-ethyl-N-methylsulfamoylamino)-2,6-difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
Reaction equation
[CH2:34]([CH3:35])[N:36]([S:37]([NH:38][CH3:39])(=[O:40])=[O:41])[c:42]1[c:43]([F:52])[c:44]([C:45](=[O:46])[OH:47])[c:48]([F:51])[cH:49][cH:50]1.[CH3:11][CH2:12][N:13]=[C:14]=[N:15][CH2:16][CH2:17][CH2:18][N:19]([CH3:20])[CH3:21].[CH3:22][O:23][c:24]1[n:25][nH:26][c:27]2[n:28][cH:29][c:30]([NH2:33])[cH:31][c:32]12.[CH3:58][CH2:59][O:60][C:61]([CH3:62])=[O:63].[Cl:64][CH2:65][Cl:66].[O:53]=[CH:54][N:55]([CH3:56])[CH3:57].[OH:1][n:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7][cH:8]2)[n:9][n:10]1>>[CH3:22][O:23][c:24]1[n:25][nH:26][c:27]2[n:28][cH:29][c:30]([NH:33][C:45]([c:44]3[c:43]([F:52])[c:42]([N:36]([CH2:34][CH3:35])[S:37]([NH:38][CH3:39])(=[O:40])=[O:41])[cH:50][cH:49][c:48]3[F:51])=[O:46])[cH:31][c:32]12
