Bromide ion → 2-(3,5-Dichloro-4'-fluoro-2-[1,1'-biphenyl]yl)-4,4-dimethyl-2-oxazoline

HRID 305717

Reaction equation

[Br-:1].[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[Cl:19][c:20]1[c:21]([C:29]2=[N:33][C:32]([CH3:34])([CH3:35])[CH2:31][O:30]2)[c:22]([O:27][CH3:28])[cH:23][c:24]([Cl:26])[cH:25]1.[F:10][c:11]1[cH:12][cH:13][c:14]([Br:15])[cH:16][cH:17]1.[F:2][c:3]1[cH:4][cH:5][c:6]([Mg+:9])[cH:7][cH:8]1.[Mg:18]>>[F:2][c:3]1[cH:4][cH:5][c:6](-[c:22]2[c:21]([C:29]3=[N:33][C:32]([CH3:34])([CH3:35])[CH2:31][O:30]3)[c:20]([Cl:19])[cH:25][c:24]([Cl:26])[cH:23]2)[cH:7][cH:8]1

Participants

Reactant 6

HCID 259Bromide ion

HCID 8028Tetrahydrofuran

HCID 99931-Bromo-4-fluorobenzene

HCID 5462224Magnesium

HCID 128028832-(2,4-Dichloro-6-methoxyphenyl)-4,4-dimethyl-2-oxazoline

HCID 178505839HCID 178505839, compound

Product 1

HCID 128028842-(3,5-Dichloro-4'-fluoro-2-[1,1'-biphenyl]yl)-4,4-dimethyl-2-oxazoline

Sources & evidence

ORD record: ord-57c8e9574b604cf5add06d981002a1a2
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Linked notes

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