Methanol → [3-[5-[2-fluoro-4-[2-oxo-5-(triazol-1-ylmethyl)-1,3-oxazolidin-3-yl]phenyl]-2-pyridinyl]-4,5-dihydro-1,2-oxazol-5-yl]methyl 1-oxidopyridin-1-ium-3-carboxylate

HRID 305747

Reaction equation

HRID 305747 reaction equation
[C:33]([c:34]1[cH:35][n+:36]([O-:40])[cH:37][cH:38][cH:39]1)(=[O:41])[OH:42].[CH3:43][CH:44]([N:45]=[C:46]=[N:47][CH:48]([CH3:49])[CH3:50])[CH3:51].[CH3:52][N:53]([CH3:54])[c:55]1[cH:56][cH:57][n:58][cH:59][cH:60]1.[CH3:66][OH:67].[CH3:68][CH2:69][O:70][CH2:71][CH3:72].[F:1][c:2]1[cH:3][c:4]([N:21]2[C:22](=[O:32])[O:23][CH:24]([CH2:26][n:27]3[n:28][n:29][cH:30][cH:31]3)[CH2:25]2)[cH:5][cH:6][c:7]1-[c:8]1[cH:9][n:10][c:11]([C:14]2=[N:15][O:16][CH:17]([CH2:19][OH:20])[CH2:18]2)[cH:12][cH:13]1.[O:61]=[CH:62][N:63]([CH3:64])[CH3:65]>>[F:1][c:2]1[cH:3][c:4]([N:21]2[C:22](=[O:32])[O:23][CH:24]([CH2:26][n:27]3[n:28][n:29][cH:30][cH:31]3)[CH2:25]2)[cH:5][cH:6][c:7]1-[c:8]1[cH:9][n:10][c:11]([C:14]2=[N:15][O:16][CH:17]([CH2:19][O:20][C:33]([c:34]3[cH:35][n+:36]([O-:40])[cH:37][cH:38][cH:39]3)=[O:41])[CH2:18]2)[cH:12][cH:13]1

Participants

8

Reactant 7

HCID 887MethanolHCID 3283Diethyl EtherHCID 6228DimethylformamideHCID 12734DiisopropylcarbodiimideHCID 142844-(Dimethylamino)pyridineHCID 16976Oxiniacic AcidHCID 184429583-[3-Fluoro-4-[6-[5-(hydroxymethyl)-4,5-dihydro-1,2-oxazol-3-yl]-3-pyridinyl]phenyl]-5-(triazol-1-ylmethyl)-1,3-oxazolidin-2-one

Product 1

HCID 178525010[3-[5-[2-fluoro-4-[2-oxo-5-(triazol-1-ylmethyl)-1,3-oxazolidin-3-yl]phenyl]-2-pyridinyl]-4,5-dihydro-1,2-oxazol-5-yl]methyl 1-oxidopyridin-1-ium-3-carboxylate

Sources & evidence

ORD record
ord-62a3158131cc4d288b18e5203b4436f1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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