Tetrahydrofuran → 5-Fluoro-2-nitrobenzoic acid methyl ester

HRID 308487

Reaction equation

HRID 308487 reaction equation
[CH2:21]1[O:22][CH2:23][CH2:24][CH2:25]1.[CH3:14][Si:15]([CH:16]=[N+:17]=[N-:18])([CH3:19])[CH3:20].[CH3:26][CH2:27][O:28][C:29](=[O:30])[CH3:31].[F:1][c:2]1[cH:3][cH:4][c:5]([N+:11](=[O:12])[O-:13])[c:6]([C:7](=[O:8])[OH:9])[cH:10]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([N+:11](=[O:12])[O-:13])[c:6]([C:7]([O:8][CH3:14])=[O:9])[cH:10]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 167693TrimethylsilyldiazomethaneHCID 27374205-Fluoro-2-nitrobenzoic acid

Product 1

HCID 51520495-Fluoro-2-nitrobenzoic acid methyl ester

Sources & evidence

ORD record
ord-f2c9717725814cf998e1d36148d94db5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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