Sodium ion → 1-Tert-butyl 3-ethyl 3-benzyl-4-oxopiperidine-1,3-dicarboxylate

HRID 311429

Reaction equation

HRID 311429 reaction equation
[Br:22][CH2:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1.[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][N:8]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:9][CH2:10][C:11]1=[O:12].[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[H-:20].[Na+:21].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1([CH2:23][c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[CH2:7][N:8]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:9][CH2:10][C:11]1=[O:12]

Participants

7

Reactant 6

HCID 923Sodium ionHCID 6228DimethylformamideHCID 7498Benzyl BromideHCID 8857Ethyl AcetateHCID 166653HydrideHCID 64208761-(1,1-Dimethylethyl) 3-ethyl 4-oxo-1,3-piperidinedicarboxylate

Product 1

HCID 541303761-Tert-butyl 3-ethyl 3-benzyl-4-oxopiperidine-1,3-dicarboxylate

Sources & evidence

ORD record
ord-e993728fea6e453989134f391debccd4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

Loading…