Dimethylformamide → 3-Bromo-6-chloro-2-fluorobenzaldehyde

HRID 311919

Reaction equation

HRID 311919 reaction equation
[Br:1][c:2]1[c:3]([F:9])[cH:4][c:5]([Cl:8])[cH:6][cH:7]1.[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[CH3:11][CH:12]([N-:13][CH:14]([CH3:15])[CH3:16])[CH3:17].[Li+:10].[O:18]=[CH:19][N:20]([CH3:21])[CH3:22]>>[Br:1][c:2]1[c:3]([F:9])[c:4]([CH:19]=[O:18])[c:5]([Cl:8])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 1372751-Bromo-4-chloro-2-fluorobenzeneHCID 5062348Diisopropylamide

Product 1

HCID 592994573-Bromo-6-chloro-2-fluorobenzaldehyde

Sources & evidence

ORD record
ord-6db726792fca4d569bf1cd86bae996be
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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