Phthalimide → 2-((2S)-2-(5-bromo-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-3-{3-[(trimethylsilyl)ethynyl]-phenyl}propyl)-1H-isoindole-1,3(2H)-dione

Reaction equation

N(C(OC(C)C)=O)=NC(OC(C)C)=O.[Br:15][C:16]1[CH:17]=[C:18]2[C:22](=[CH:23][CH:24]=1)[C:21](=[O:25])[N:20]([C@@H:26]([CH2:29][C:30]1[CH:35]=[CH:34][CH:33]=[C:32]([C:36]#[C:37][Si:38]([CH3:41])([CH3:40])[CH3:39])[CH:31]=1)[CH2:27]O)[CH2:19]2.[C:42]1(=[O:52])[NH:46][C:45](=[O:47])[C:44]2=[CH:48][CH:49]=[CH:50][CH:51]=[C:43]12.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>O1CCCC1>[Br:15][C:16]1[CH:17]=[C:18]2[C:22](=[CH:23][CH:24]=1)[C:21](=[O:25])[N:20]([C@@H:26]([CH2:29][C:30]1[CH:35]=[CH:34][CH:33]=[C:32]([C:36]#[C:37][Si:38]([CH3:41])([CH3:40])[CH3:39])[CH:31]=1)[CH2:27][N:46]1[C:42](=[O:52])[C:43]3[C:44](=[CH:48][CH:49]=[CH:50][CH:51]=3)[C:45]1=[O:47])[CH2:19]2