Tetrahydrofuran → 6,6-Dioxo-5,6-dihydro-6lambda6-thia-4,5-diaza-chrysene-12-carboxylic acid (2-piperidin-1-yl-ethyl)-amide

Reaction equation

[N:1]1([CH2:7][CH2:8][NH2:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Br[C:11]1[CH:12]=[C:13]2[C:22](=[C:23]3[C:28]=1[CH:27]=[CH:26][CH:25]=[N:24]3)[NH:21][S:20](=[O:30])(=[O:29])[C:19]1[C:14]2=[CH:15][CH:16]=[CH:17][CH:18]=1.C1CCN2C(=NCCC2)CC1.C1C[O:45][CH2:44]C1>>[N:1]1([CH2:7][CH2:8][NH:9][C:44]([C:11]2[CH:12]=[C:13]3[C:22](=[C:23]4[C:28]=2[CH:27]=[CH:26][CH:25]=[N:24]4)[NH:21][S:20](=[O:30])(=[O:29])[C:19]2[C:14]3=[CH:15][CH:16]=[CH:17][CH:18]=2)=[O:45])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1