Diisopropylethylamine → tert-butyl-N-[1-oxo-1-[[1-[2-(1,3-thiazol-4-yl)ethynyl]isoquinolin-3-yl]-amino]propan-2-yl]carbamate

Reaction equation

[C:1]([O:5][C:6](=[O:25])[NH:7][CH:8]([CH3:24])[C:9]([NH:11][C:12]1[N:13]=[C:14]([C:22]#[CH:23])[C:15]2[C:20]([CH:21]=1)=[CH:19][CH:18]=[CH:17][CH:16]=2)=[O:10])([CH3:4])([CH3:3])[CH3:2].Br[C:27]1[N:28]=[CH:29][S:30][CH:31]=1.CCN(C(C)C)C(C)C>CN1C(=O)CCC1.[Cu]I.Cl[Pd](Cl)([P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1>[C:1]([O:5][C:6](=[O:25])[NH:7][CH:8]([CH3:24])[C:9](=[O:10])[NH:11][C:12]1[N:13]=[C:14]([C:22]#[C:23][C:27]2[N:28]=[CH:29][S:30][CH:31]=2)[C:15]2[C:20]([CH:21]=1)=[CH:19][CH:18]=[CH:17][CH:16]=2)([CH3:4])([CH3:3])[CH3:2]