Hydrochloric Acid → (R)-2-[(R)-2-(6-Bromo-3-fluoro-pyridin-2-yl)-2-(4-nitro-benzenesulfonylamino)-propoxy]-3,3,3-trifluoro-2-methyl-propionic acid ethyl ester

Reaction equation

[CH2:1]([O:3][C:4](=[O:12])[C@:5]([OH:11])([CH3:10])[C:6]([F:9])([F:8])[F:7])[CH3:2].CC([O-])(C)C.[K+].[Br:19][C:20]1[N:25]=[C:24]([C:26]2([CH3:41])[CH2:28][N@@:27]2[S:29]([C:32]2[CH:37]=[CH:36][C:35]([N+:38]([O-:40])=[O:39])=[CH:34][CH:33]=2)(=[O:31])=[O:30])[C:23]([F:42])=[CH:22][CH:21]=1.Cl>CN(C=O)C.[Cl-].[Na+].O.CC(OC)(C)C>[CH2:1]([O:3][C:4](=[O:12])[C@:5]([O:11][CH2:41][C@@:26]([C:24]1[C:23]([F:42])=[CH:22][CH:21]=[C:20]([Br:19])[N:25]=1)([NH:27][S:29]([C:32]1[CH:37]=[CH:36][C:35]([N+:38]([O-:40])=[O:39])=[CH:34][CH:33]=1)(=[O:30])=[O:31])[CH3:28])([CH3:10])[C:6]([F:7])([F:8])[F:9])[CH3:2]