Iodoethane → 3,5-Diethoxybenzaldehyde
Reaction equation
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][C:11]=1C)[CH:7]=[O:8])[CH3:2].[OH:13][C:14]1C=C(C=C(O)[CH:21]=1)C=O.C(I)C.C([O-])([O-])=O.[K+].[K+]>CN(C=O)C>[CH2:14]([O:13][C:10]1[CH:9]=[C:6]([CH:5]=[C:4]([O:3][CH2:1][CH3:2])[CH:11]=1)[CH:7]=[O:8])[CH3:21]Participants
6
Reactant 4
Product 1
Reagents, catalysts & solvents 1
Procedure
The title compound was prepared analogously to 3-ethoxy-4-methyl-benzaldehyde (intermediate B21, vide infra) by reaction of 3,5-dihydroxybenzaldehyde with ethyl iodide in DMF using K2CO3 as base.
Sources & evidence
- ORD record
- ord-6e1b1b9a97b6446b8d3185117c6cce95
- Source dataset
- uspto-grants-2011_05
- Patent number
- US07939661B2
Reaction notes
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