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Hydrochloric Acid → Tromethamine hydrochloride

HRID 59057
Notes
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Reaction equation

HRID 59057 reaction equation
[CH2:1]([OH:8])[C:2]([NH2:7])([CH2:5][OH:6])[CH2:3][OH:4].[ClH:9]>O>[CH2:1]([OH:8])[C:2]([NH2:7])([CH2:5][OH:6])[CH2:3][OH:4].[ClH:9]
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 6503Tris(hydroxymethyl)aminomethane

Product 1

HCID 93573Tromethamine hydrochloride

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

6.057 g of Tris base(molecular weight 121.14 g) was accurately weighed into a 1 litre volumetric flask. 800 ml of deionised water was added, it's pH adjusted to pH8 with concentrated HCl and then diluted to volume with de-ionised water. Buffer was stored at 4° C.

Workup

  1. customBuffer was stored at 4° C.

Sources & evidence

ORD record
ord-705066c7c5074f4cb9cba6150d1fa99d
Source dataset
uspto-grants-2016_09
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US09439936B2

Reaction notes

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On this pageParticipantsProcedureWorkupSources & evidenceReaction notes