HomeMCPWorkbenchSkills
HomeWorkbenchNotificationsMe
llms.txt · MCP GuidePrivacy Policy · Terms of Service · Supportv1.8.0
  1. Home
  2. /Reaction

Creatine → Creatine

HRID 613450
Notes
Print preview

Reaction equation

HRID 613450 reaction equation
[C:1]([OH:6])(=[O:5])[C:2](C)=O.C([O-])(=O)C(C)=O.[Mg+2].C([O-])(=O)C(C)=O.C([O-])(=O)C(C)=O.[K+].C([O-])(=O)C(C)=O.[Ca+2].C([O-])(=O)C(C)=O.C([O-])(=O)C(C)=O.[Na+].[Na].C([O-])(=O)C(C)=O.C(NCC(O)=O)(=O)C(C)=O.C([CH:69]([N:73]([C:75](=[NH:77])[NH2:76])C)C(O)=O)(=O)C(C)=O.O=C(C[N:82]([C:84](=[NH:86])[NH2:85])C)O>O.C(O)(=O)C>[O:5]=[C:1]([CH2:2][N:73]([C:75](=[NH:76])[NH2:77])[CH3:69])[OH:6].[O:5]=[C:1]([CH2:2][NH:85][C:84](=[NH:82])[NH2:86])[OH:6]
ParticipantsProcedureSources & evidenceReaction notes

Participants

14

Reactant 10

HCID 586Creatine4×HCID 1060Pyruvic Acid3×HCID 107735Pyruvate3×HCID 5360545Sodium2×HCID 6451625PyruvoylglycineHCID 9859191Calcium pyruvateHCID 10219827
Magnesium pyruvate
HCID 23662274Sodium pyruvate
HCID 23678876Propanoic acid, 2-oxo-, potassium salt (1:1)
HCID 131721533Pyruvyl-creatine

Product 2

HCID 586CreatineHCID 178513022HCID 178513022, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 962WaterSolvent2×

Procedure

Pyruvic acid is a colorless liquid with an odor resembling that of acetic acid and has a melting point of 13° C. Pyruvic acid is an intermediate in the breakdown of sugars to alcohol by yeast. The mineral salts of pyruvic acid, such as magnesium pyruvate, potassium pyruvate or calcium pyruvate or mixtures thereof are useful in the present invention. Sodium pyruvate is not especially preferred as it is known that sodium is associated with various negative medical conditions such as high blood pressure, water retention and heart disease. Further, certain athletes, such as bodybuilders, desire to present a defined visual image of their body which shows muscle definition and thus, the water retention properties of the sodium salt are not beneficial. Pyruvate precursors in the form of pyruvamides or pyruvyl-amino acids are also useful in the present invention. Pyruvyl-glycine is representative of the useful pyruvyl-amino acids. Another form of pyruvate precursor is pyruvyl-creatine, wherein pyruvate is bonded to creatine either covalently or ionically. Creatine or methylguanidineacetic acid has the chemical formula: ##STR2## and is present in the muscle tissue of vertebrates. It plays an important part in the cycle of chemical changes involving muscular contraction. Normally, creatine is the form in which creatine is excreted. Creatine is formed in the body by the methylation (by methionine) of glycocyamine.

Sources & evidence

ORD record
ord-3c45540003774589824d60aeb4717e18
Source dataset
uspto-grants-1999_12
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US06008252

Reaction notes

Loading…

On this pageParticipantsProcedureSources & evidenceReaction notes