Methane → HCID 21243167, compound

HRID 621424Notes

Reaction equation

HRID 621424 reaction equation
[NH2:1][C:2]1[N:7]=[C:6](N)[N:5]=[C:4]([NH:9][CH:10]2[CH2:12][CH2:11]2)[N:3]=1.C(N([CH2:18][CH3:19])CC)C.[CH4:20].[O:21]1[CH2:25][CH2:24][CH2:23][CH2:22]1>>[CH:10]1([NH:9][C:4]2[N:3]=[C:2]([NH:1][C:22](=[O:21])[CH2:23][CH2:24][CH2:25][CH2:20][CH2:18][CH3:19])[N:7]=[CH:6][N:5]=2)[CH2:12][CH2:11]1

Participants

5

Reactant 4

HCID 297MethaneHCID 8028Tetrahydrofuran2×HCID 8471TriethylamineHCID 47866Cyromazine

Product 1

HCID 21243167HCID 21243167, compound

Procedure

To a suspension of 33.2 g of 2,4-diamino-6-cyclopropylamino-1,3,5-triazine and 30.3 g of triethylamine in 800 ml of tetrahydrofuran are slowly added dropwise, at 60° C., 50.9 g of oenanthic acid anhydride dissolved in 100 ml of tetrahydrofuran. The reaction mixture is subsequently stirred overnight at 60° C.; active charcoal is then added and the mixture is filtered hot. The filtrate is concentrated by evaporation, and isopropanol is added. The product is obtained, after filtration and drying, in the form of a white crystalline powder having a melting point of 195°-197° C.

Workup

  1. additionare slowly added dropwise, at 60° C.
  2. filtrationthe mixture is filtered hot
  3. concentrationThe filtrate is concentrated by evaporation, and isopropanol
  4. additionis added
  5. customThe product is obtained
  6. filtrationafter filtration
  7. customdrying, in the form of a white crystalline powder

Sources & evidence

ORD record
ord-ef5e7859ad19486db3974ffa43406063
Source dataset
uspto-grants-1989_04
Patent number
US04824845

Reaction notes

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