Hydrochloric Acid → L-Ascorbic Acid

HRID 650695

Reaction equation

HRID 650695 reaction equation
C(O)C.[Na].[CH2:5]([OH:17])[C@H:6]([OH:16])[C@@H:7](O)[C@H:8]([OH:14])[C:9]([C:11]([OH:13])=[O:12])=[O:10].Cl>CC(C)=O>[O:12]=[C:11]1[O:13][C@H:7]([C@H:6]([CH2:5][OH:17])[OH:16])[C:8]([OH:14])=[C:9]1[OH:10]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 1024242-keto-L-Gulonic acidHCID 5360545Sodium

Product 1

HCID 54670067L-Ascorbic Acid

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Japanese laid-open application 58-177986 describes a process which includes the addition of ethanol and acetone to the sodium salt of 2-keto-L-gulonic acid, neutralization with hydrochloric acid, separating off the sodium chloride which is precipitated out by filtration and then holding the reaction mixture at temperatures in the range from 25° C. to 75° C., as a result of which L-ascorbic acid is obtained.

Workup

  1. customseparating off the sodium chloride which
  2. customis precipitated out by filtration
  3. customfrom 25° C. to 75° C.

Sources & evidence

ORD record
ord-ac1c7694d4e7425fa432c78686514ebd
Source dataset
uspto-grants-2001_08
Patent number
US06274744B1

Linked notes

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