Methanol → N-[5-(2,2-dimethyl-1,3-dioxolan-4-yl)pyrazin-2-yl]-4-methylsulfanyl-2-[3-oxo-7-(trifluoromethyl)-1H-isoindol-2-yl]butanamide
Reaction equation
[CH2:51]([Cl:52])[Cl:53].[CH3:1][S:2][CH2:3][CH2:4][CH:5]([C:6](=[O:7])[OH:8])[N:9]1[C:10](=[O:22])[c:11]2[cH:12][cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[c:16]2[CH2:17]1.[CH3:29][C:30]1([CH3:42])[O:31][CH2:32][CH:33]([c:35]2[n:36][cH:37][c:38]([NH2:41])[n:39][cH:40]2)[O:34]1.[CH3:54][N:55]([CH3:56])[CH:57]=[O:58].[CH3:59][OH:60].[Cl:23][C:24]([C:25]([Cl:26])=[O:27])=[O:28].[n:43]1[c:44]([CH3:45])[cH:46][cH:47][cH:48][c:49]1[CH3:50]>>[CH3:1][S:2][CH2:3][CH2:4][CH:5]([C:6](=[O:7])[NH:41][c:38]1[cH:37][n:36][c:35]([CH:33]2[CH2:32][O:31][C:30]([CH3:29])([CH3:42])[O:34]2)[cH:40][n:39]1)[N:9]1[C:10](=[O:22])[c:11]2[cH:12][cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[c:16]2[CH2:17]1
