4-Methylmorpholine → 2-Bromo-4-methyl-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide

HRID 675918

Reaction equation

HRID 675918 reaction equation
[Br:1][c:2]1[s:3][c:4]([C:8](=[O:9])[OH:10])[c:5]([CH3:7])[n:6]1.[CH3:11][N:12]1[CH2:13][CH2:14][O:15][CH2:16][CH2:17]1.[Cl:18][C:19]([O:20][CH2:21][CH:22]([CH3:23])[CH3:24])=[O:25].[NH2:26][CH2:27][c:28]1[cH:29][n:30][cH:31][cH:32][cH:33]1.[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1>>[Br:1][c:2]1[s:3][c:4]([C:8](=[O:10])[NH:26][CH2:27][c:28]2[cH:29][n:30][cH:31][cH:32][cH:33]2)[c:5]([CH3:7])[n:6]1

Participants

6

Reactant 5

HCID 79724-MethylmorpholineHCID 8028TetrahydrofuranHCID 310183-PyridinemethanamineHCID 62365Isobutyl chloroformateHCID 28240582-Bromo-4-methyl-1,3-thiazole-5-carboxylic acid

Product 1

HCID 666315502-Bromo-4-methyl-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide

Sources & evidence

ORD record
ord-c61ea0d2262542b49af7d9717c7f5e65
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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