Acetate → Ethyl 3-[2-amino-5-(trifluoromethyl)phenyl]prop-2-enoate

HRID 680559

Reaction equation

HRID 680559 reaction equation
[Br:1][c:2]1[c:3]([NH2:4])[cH:5][cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1.[C:20]([CH:21]=[CH2:22])(=[O:23])[O:24][CH2:25][CH3:26].[C:32]([O-:33])(=[O:34])[CH3:35].[C:37]([O-:38])(=[O:39])[CH3:40].[CH3:13][CH2:14][N:15]([CH2:16][CH3:17])[CH2:18][CH3:19].[O:27]=[CH:28][N:29]([CH3:30])[CH3:31].[Pd+2:36]>>[c:2]1([CH:22]=[CH:21][C:20](=[O:23])[O:24][CH2:25][CH3:26])[c:3]([NH2:4])[cH:5][cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1

Participants

7

Reactant 6

HCID 175Acetate2×HCID 6228DimethylformamideHCID 8471TriethylamineHCID 8821Ethyl AcrylateHCID 938992-Bromo-4-trifluoromethylanilineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

Product 1

HCID 91364508Ethyl 3-[2-amino-5-(trifluoromethyl)phenyl]prop-2-enoate

Sources & evidence

ORD record
ord-c0ba9cd49ee446adac1426b68e3af664
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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