Sodium ion → (5-Bromo-2-(methylthio)pyrimidin-4-yl)methanol

HRID 686545

Reaction equation

HRID 686545 reaction equation
[BH4-:24].[Br:12][c:13]1[c:14]([C:21](=[O:22])[OH:23])[n:15][c:16]([S:19][CH3:20])[n:17][cH:18]1.[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:31][C:32]#[N:33].[Cl:34][CH2:35][Cl:36].[Cl:6][C:7]([C:8]([Cl:9])=[O:10])=[O:11].[Na+:25].[O:1]=[CH:2][N:3]([CH3:4])[CH3:5]>>[Br:12][c:13]1[c:14]([CH2:21][OH:22])[n:15][c:16]([S:19][CH3:20])[n:17][cH:18]1

Participants

9

Reactant 8

HCID 923Sodium ionHCID 6228DimethylformamideHCID 6342AcetonitrileHCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 28123BorohydrideHCID 65578Oxalyl chlorideHCID 2917865-Bromo-2-(methylthio)pyrimidine-4-carboxylic Acid

Product 1

HCID 66524860(5-Bromo-2-(methylthio)pyrimidin-4-yl)methanol

Sources & evidence

ORD record
ord-b8f48282ff454f1bac2423cd49ef59b3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

Loading…