Tetrahydrofuran → N-[2-(3-chlorophenyl)-1-(4-chlorophenyl)but-3-enyl]-N-(dicyclopropylmethyl)prop-2-enamide

HRID 689799

Reaction equation

HRID 689799 reaction equation
[C:34]([CH:35]=[CH2:36])(=[O:37])[Cl:38].[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[CH3:39][CH2:40][O:41][C:42](=[O:43])[CH3:44].[Cl:1][c:2]1[cH:3][c:4]([CH:8]([CH:9]([NH:10][CH:11]([CH:12]2[CH2:13][CH2:14]2)[CH:15]2[CH2:16][CH2:17]2)[c:18]2[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]2)[CH:25]=[CH2:26])[cH:5][cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][c:4]([CH:8]([CH:9]([N:10]([CH:11]([CH:12]2[CH2:13][CH2:14]2)[CH:15]2[CH2:16][CH2:17]2)[C:34]([CH:35]=[CH2:36])=[O:37])[c:18]2[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]2)[CH:25]=[CH2:26])[cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 13140Acryloyl chlorideHCID 768348362-(3-chlorophenyl)-1-(4-chlorophenyl)-N-(dicyclopropylmethyl)but-3-en-1-amine

Product 1

HCID 70644333N-[2-(3-chlorophenyl)-1-(4-chlorophenyl)but-3-enyl]-N-(dicyclopropylmethyl)prop-2-enamide

Sources & evidence

ORD record
ord-497c88cdf1b54543bd2f9ffa86e579a4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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