Acetone → Tert-butyl 5-chloro-7-fluoro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carbonyl(methyl)carbamate

HRID 698298

Reaction equation

HRID 698298 reaction equation
[C-:46]#[N:47].[CH2:48]([N+:49]([CH2:50][CH2:51][CH2:52][CH3:53])([CH2:54][CH2:55][CH2:56][CH3:57])[CH2:58][CH2:59][CH2:60][CH3:61])[CH2:62][CH2:63][CH3:64].[CH2:65]1[O:66][CH2:67][CH2:68][CH2:69]1.[CH3:13][C:14](=[O:15])[CH3:16].[Cl:17][c:18]1[cH:19][c:20]2[n:21]([c:22]([Cl:24])[cH:23]1)[n:25][c:26](-[c:39]1[cH:40][cH:41][c:42]([F:45])[cH:43][cH:44]1)[c:27]2[C:28](=[O:29])[N:30]([C:31]([O:32][C:33]([CH3:34])([CH3:35])[CH3:36])=[O:37])[CH3:38].[F:1][c:2]1[c:3]([F:4])[c:5]([F:6])[c:7]([F:8])[c:9]([F:10])[c:11]1[F:12]>>[F:1][c:22]1[n:21]2[c:20]([cH:19][c:18]([Cl:17])[cH:23]1)[c:27]([C:28](=[O:29])[N:30]([C:31]([O:32][C:33]([CH3:34])([CH3:35])[CH3:36])=[O:37])[CH3:38])[c:26](-[c:39]1[cH:40][cH:41][c:42]([F:45])[cH:43][cH:44]1)[n:25]2

Participants

7

Reactant 6

HCID 180AcetoneHCID 5975CyanideHCID 8028TetrahydrofuranHCID 9805HexafluorobenzeneHCID 16028TetrabutylammoniumHCID 59233773Tert-butyl 5,7-dichloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carbonyl(methyl)carbamate

Product 1

HCID 59233766Tert-butyl 5-chloro-7-fluoro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carbonyl(methyl)carbamate

Sources & evidence

ORD record
ord-2361207431934961bdb02dbf0f3e57cd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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