4-Methylmorpholine → [1-(6-{5-[4-(6-{2-[4-Cyano-1-(2-methoxycarbonylamino-3-methyl-butyryl)-pyrrolidin-2-yl]-3h-imidazol-4-yl}-naphthalen-2-yl)-phenyl]-1h-imidazol-2-yl}-5-aza-spiro[2.4]heptane-5-carbonyl)-2-methyl-propyl]-carbamic acid methyl ester

Reaction equation

[CH3:1][O:2][C:3]([NH:5][CH:6]([CH:10]([CH3:12])[CH3:11])[C:7](O)=[O:8])=[O:4].C1C=CC2N(O)N=NC=2C=1.Cl.Cl.Cl.[CH3:26][O:27][C:28](=[O:76])[NH:29][CH:30]([C:34]([N:36]1[CH:42]([C:43]2[NH:44][C:45]([C:48]3[CH:53]=[CH:52][C:51]([C:54]4[CH:63]=[CH:62][C:61]5[C:56](=[CH:57][CH:58]=[C:59]([C:64]6[NH:65][C:66]([CH:69]7[CH2:73][CH:72]([C:74]#[N:75])[CH2:71][NH:70]7)=[N:67][CH:68]=6)[CH:60]=5)[CH:55]=4)=[CH:50][CH:49]=3)=[CH:46][N:47]=2)[CH2:41][C:38]2([CH2:40][CH2:39]2)[CH2:37]1)=[O:35])[CH:31]([CH3:33])[CH3:32].CN1CCOCC1>CN(C=O)C.CCOC(C)=O>[CH3:26][O:27][C:28](=[O:76])[NH:29][CH:30]([C:34]([N:36]1[CH:42]([C:43]2[NH:44][C:45]([C:48]3[CH:49]=[CH:50][C:51]([C:54]4[CH:63]=[CH:62][C:61]5[C:56](=[CH:57][CH:58]=[C:59]([C:64]6[NH:65][C:66]([CH:69]7[CH2:73][CH:72]([C:74]#[N:75])[CH2:71][N:70]7[C:7](=[O:8])[CH:6]([NH:5][C:3]([O:2][CH3:1])=[O:4])[CH:10]([CH3:12])[CH3:11])=[N:67][CH:68]=6)[CH:60]=5)[CH:55]=4)=[CH:52][CH:53]=3)=[CH:46][N:47]=2)[CH2:41][C:38]2([CH2:39][CH2:40]2)[CH2:37]1)=[O:35])[CH:31]([CH3:33])[CH3:32]