Piperazine → 1-[6-(Trifluoromethyl)pyridin-2-yl]piperazine
Reaction equation
[CH2:12]1[CH2:13][NH:14][CH2:15][CH2:16][NH:17]1.[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[Cl:1][c:2]1[n:3][c:4]([C:8]([F:9])([F:10])[F:11])[cH:5][cH:6][cH:7]1.[O:25]=[CH:26][N:27]([CH3:28])[CH3:29]>>[c:2]1([N:14]2[CH2:13][CH2:12][NH:17][CH2:16][CH2:15]2)[n:3][c:4]([C:8]([F:9])([F:10])[F:11])[cH:5][cH:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-4b2d9c4c1c9a4b979ff65cdfd4d4787e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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