Bromobenzene → HCID 13976522, compound

HRID 80310

Reaction equation

HRID 80310 reaction equation
C1(C2C=CC=CC=2CO)C2C(=CC=CC=2)C=CC=1.[Mg].Br[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1.[N:27]1[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=1[C:33]([C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][N:36]=1)=[O:34]>>[N:27]1[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=1[C:33]([C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][N:36]=1)([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[OH:34]

Participants

5

Reactant 4

HCID 7961BromobenzeneHCID 88065Bis(2-pyridyl) ketoneHCID 5462224MagnesiumHCID 57154374[(Naphthyl)phenyl]methanol

Product 1

HCID 13976522HCID 13976522, compound

Procedure

With the same method as for Compound 13, a Grignard reagent was prepared from magnesium (Wako Pure Chemical Industries, Ltd.) and bromobenzene (Wako Pure Chemical Industries, Ltd.), and di-2-pyridyl ketone (Aldrich) was allowed to react with the reagent, to thereby obtain the title compound.

Workup

  1. customto react with the reagent

Sources & evidence

ORD record
ord-f66ee864a4874158ae2ad1549b245738
Source dataset
uspto-grants-2014_09
Patent number
US08846012B2

Linked notes

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