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Bromide ion → 2,2,2-trifluoro-N-(4-formyl-3,5-dimethylphenyl)acetamide

HRID 807112
Notes
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Reaction equation

HRID 807112 reaction equation
[Br-:19].[Br:1][c:2]1[c:3]([CH3:16])[cH:4][c:5]([NH:9][C:10]([C:11]([F:12])([F:13])[F:14])=[O:15])[cH:6][c:7]1[CH3:8].[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH2:41]1[CH2:42][CH2:43][CH2:44][CH2:45][CH2:46]1.[CH3:36][CH2:37][O:38][CH2:39][CH3:40].[CH:21]([Li:22])([CH2:23][CH3:24])[CH3:25].[Li+:20].[Li:17][CH3:18].[O:26]=[CH:27][N:28]([CH3:29])[CH3:30]>>[c:2]1([CH:27]=[O:26])[c:3]([CH3:16])[cH:4][c:5]([NH:9][C:10]([C:11]([F:12])([F:13])[F:14])=[O:15])[cH:6][c:7]1[CH3:8]
ParticipantsSources & evidenceReaction notes

Participants

10

Reactant 9

HCID 259Bromide ionHCID 3283Diethyl EtherHCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 8078CyclohexaneHCID 28486Lithium CationHCID 21336351N-(4-bromo-3,5-dimethylphenyl)-2,2,2-trifluoroacetamide

Sources & evidence

ORD record
ord-56f6ad6e7d574aff847b5f342ccaa1b1
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes
HCID 178418348
HCID 178418348, compound
HCID 178418400CID 53628100

Product 1

HCID 866328212,2,2-trifluoro-N-(4-formyl-3,5-dimethylphenyl)acetamide