Chloride → 2-Methyl-2-(4-fluorophenyl)-5-[2-(2-pyridinyl)ethenyl]-3(2H)-furanone

HRID 811645

Reaction equation

HRID 811645 reaction equation
[CH3:37][CH2:38][OH:39].[CH3:9][C:10]1([c:17]2[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]2)[O:11][C:12]([CH3:16])=[CH:13][C:14]1=[O:15].[Cl-:36].[N:24]12[CH2:25][CH2:26][CH2:27][N:28]=[C:29]1[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]2.[Na+:35].[n:1]1[c:2]([CH:7]=[O:8])[cH:3][cH:4][cH:5][cH:6]1>>[n:1]1[c:2]([CH:7]=[CH:16][C:12]2=[CH:13][C:14](=[O:15])[C:10]([CH3:9])([c:17]3[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]3)[O:11]2)[cH:3][cH:4][cH:5][cH:6]1

Participants

7

Reactant 6

HCID 312ChlorideHCID 702EthanolHCID 923Sodium ionHCID 142732-PyridinecarboxaldehydeHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 150867042-(4-Fluorophenyl)-2,5-dimethylfuran-3(2H)-one

Product 1

HCID 541443362-Methyl-2-(4-fluorophenyl)-5-[2-(2-pyridinyl)ethenyl]-3(2H)-furanone

Sources & evidence

ORD record
ord-f54fbfad88b9439497fc918552d72e97
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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