Chloride → 2-Bromo-2',4'-difluoroacetophenone
Reaction equation
[Al+3:15].[Br:9][CH2:10][C:11](=[O:12])[Br:13].[Cl-:14].[Cl-:16].[Cl-:17].[Cl:19][CH2:20][Cl:21].[ClH:18].[F:1][c:2]1[cH:3][cH:4][cH:5][c:6]([F:7])[cH:8]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:11]([CH2:10][Br:9])=[O:12])[c:6]([F:7])[cH:8]1Participants
7
Sources & evidence
- ORD record
- ord-86cf25ac17f54b22a6cfb70d07f2646c
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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