Dimethylformamide → 6-Amino-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-vinyl-pyrimidine-4-carboxylic acid butyl ester

HRID 821100

Reaction equation

[I:23][CH2:24][CH2:25][CH2:26][CH3:27].[Li+:28].[Li+:29].[NH2:1][c:2]1[c:3]([CH:21]=[CH2:22])[c:4]([C:18](=[O:19])[OH:20])[n:5][c:6](-[c:8]2[c:9]([F:17])[c:10]([O:15][CH3:16])[c:11]([Cl:14])[cH:12][cH:13]2)[n:7]1.[O-:30][C:31](=[O:32])[O-:33].[O:34]=[CH:35][N:36]([CH3:37])[CH3:38]>>[NH2:1][c:2]1[c:3]([CH:21]=[CH2:22])[c:4]([C:18]([O:19][CH2:24][CH2:25][CH2:26][CH3:27])=[O:20])[n:5][c:6](-[c:8]2[c:9]([F:17])[c:10]([O:15][CH3:16])[c:11]([Cl:14])[cH:12][cH:13]2)[n:7]1