Hydrochloric Acid → 3-(5-Bromo-2-benzofuran-1(3H)-ylidene)-1,3-dihydro-2H-indol-2-one

HRID 86055

Reaction equation

HRID 86055 reaction equation
[Br:26][c:27]1[cH:28][c:29]2[c:34]([cH:35][cH:36]1)[C:32](=[O:33])[O:31][CH2:30]2.[CH2:21]1[O:22][CH2:23][CH2:24][CH2:25]1.[CH2:38]([CH2:39][O:40][CH3:41])[O:42][CH3:43].[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:12][Si:13]([N-:14][Si:15]([CH3:16])([CH3:17])[CH3:18])([CH3:19])[CH3:20].[ClH:37].[Li+:11].[NH:1]1[C:2](=[O:10])[CH2:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]21.[OH2:44]>>[NH:1]1[C:2](=[O:10])[C:3](=[C:32]2[O:31][CH2:30][c:29]3[cH:28][c:27]([Br:26])[cH:36][cH:35][c:34]32)[c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]21

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 962WaterHCID 8028Tetrahydrofuran2×HCID 80711,2-DimethoxyethaneHCID 28486Lithium ionHCID 321710OxindoleHCID 6031445-BromophthalideHCID 3280088Npc316347

Product 1

HCID 696592423-(5-Bromo-2-benzofuran-1(3H)-ylidene)-1,3-dihydro-2H-indol-2-one

Sources & evidence

ORD record
ord-30027e136c8f40e6a29012b16751e3c7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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