Dimethylformamide → Ethyl 6,8-dichloro-7-(4-(4-chlorophenethylcarbamoyl)phenoxy)chroman-4-carboxylate

HRID 86872

Reaction equation

HRID 86872 reaction equation
[CH:44]([N:45]([CH:46]([CH3:47])[CH3:48])[CH2:49][CH3:50])([CH3:51])[CH3:52].[Cl:1][c:2]1[cH:3][c:4]2[c:9]([c:10]([Cl:22])[c:11]1[O:12][c:13]1[cH:14][cH:15][c:16]([C:17](=[O:18])[OH:19])[cH:20][cH:21]1)[O:8][CH2:7][CH2:6][CH:5]2[C:23](=[O:24])[O:25][CH2:26][CH3:27].[Cl:28][C:29]([C:30]([Cl:31])=[O:32])=[O:33].[Cl:34][c:35]1[cH:36][cH:37][c:38]([CH2:41][CH2:42][NH2:43])[cH:39][cH:40]1.[Cl:53][CH2:54][Cl:55].[O:56]=[CH:57][N:58]([CH3:59])[CH3:60]>>[Cl:1][c:2]1[cH:3][c:4]2[c:9]([c:10]([Cl:22])[c:11]1[O:12][c:13]1[cH:14][cH:15][c:16]([C:17](=[O:19])[NH:43][CH2:42][CH2:41][c:38]3[cH:37][cH:36][c:35]([Cl:34])[cH:40][cH:39]3)[cH:20][cH:21]1)[O:8][CH2:7][CH2:6][CH:5]2[C:23](=[O:24])[O:25][CH2:26][CH3:27]

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 65578Oxalyl chlorideHCID 674302-(4-Chlorophenyl)ethylamineHCID 81531DiisopropylethylamineHCID 670803034-(6,8-Dichloro-4-(ethoxycarbonyl)chroman-7-yloxy)benzoic acid

Product 1

HCID 67080461Ethyl 6,8-dichloro-7-(4-(4-chlorophenethylcarbamoyl)phenoxy)chroman-4-carboxylate

Sources & evidence

ORD record
ord-096292a2254b4f2cb6fdcc0652f0f610
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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