Dimethylformamide → Hydrochloric Acid

HRID 87796

Reaction equation

HRID 87796 reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:9]([cH:10][c:11]1[O:12][CH3:13])[NH:8][C:7](=[O:14])[CH2:6]2.[Cl:16][c:17]1[n:18][cH:19][n:20][c:21]2[cH:22][c:23]([O:29][CH2:30][CH2:31][O:32][CH3:33])[c:24]([O:27][CH3:28])[cH:25][c:26]12.[H-:15].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:9]([cH:10][c:11]1[O:12][CH3:13])[NH:8][C:7](=[O:14])[CH:6]2[c:17]1[n:18][cH:19][n:20][c:21]2[cH:22][c:23]([O:29][CH2:30][CH2:31][O:32][CH3:33])[c:24]([O:27][CH3:28])[cH:25][c:26]12.[ClH:16]

Participants

7

Reactant 5

HCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 166653HydrideHCID 2229935,6-Dimethoxyindolin-2-oneHCID 107306534-Chloro-6-methoxy-7-(2-methoxyethoxy)quinazoline

Product 2

HCID 313Hydrochloric AcidHCID 217172375,6-Dimethoxy-3-[6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]-1,3-dihydroindol-2-one

Sources & evidence

ORD record
ord-03a8b60e11d4486391942cc6e7d7363f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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