Dimethylformamide → [3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-piperidin-1-ylpropan-2-yl] 4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxylate

HRID 87826

Reaction equation

HRID 87826 reaction equation
[CH2:45]1[CH2:46][CH2:47][NH:48][CH2:49][CH2:50]1.[CH3:1][c:2]1[cH:3][c:4]([CH2:11][CH:12]([C:13](=[O:14])[OH:15])[O:16][C:17](=[O:18])[N:19]2[CH2:20][CH2:21][CH:22]([c:25]3[c:26](=[O:35])[nH:27][c:28]4[cH:29][cH:30][cH:31][cH:32][c:33]4[cH:34]3)[CH2:23][CH2:24]2)[cH:5][c:6]2[cH:7][n:8][nH:9][c:10]12.[CH3:84][N:85]([CH3:86])[CH:87]=[O:88].[CH:36]([N:37]([CH:38]([CH3:39])[CH3:40])[CH2:41][CH3:42])([CH3:43])[CH3:44].[Cl:89][CH2:90][Cl:91].[P-:51]([F:52])([F:53])([F:54])([F:55])([F:56])[F:57].[n:58]1([O:59][P+:60]([N:61]2[CH2:62][CH2:63][CH2:64][CH2:65]2)([N:66]2[CH2:67][CH2:68][CH2:69][CH2:70]2)[N:71]2[CH2:72][CH2:73][CH2:74][CH2:75]2)[c:76]2[cH:77][cH:78][cH:79][cH:80][c:81]2[n:82][n:83]1>>[CH3:1][c:2]1[cH:3][c:4]([CH2:11][CH:12]([C:13](=[O:14])[N:48]2[CH2:47][CH2:46][CH2:45][CH2:50][CH2:49]2)[O:16][C:17](=[O:18])[N:19]2[CH2:20][CH2:21][CH:22]([c:25]3[c:26](=[O:35])[nH:27][c:28]4[cH:29][cH:30][cH:31][cH:32][c:33]4[cH:34]3)[CH2:23][CH2:24]2)[cH:5][c:6]2[cH:7][n:8][nH:9][c:10]12

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 8082PiperidineHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 2724700Benzotriazol-1-yl-oxytripyrrolidinophosphoniumHCID 684632393-(7-methyl-1H-indazol-5-yl)-2-[4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carbonyl]oxypropanoic acid

Product 1

HCID 68462497[3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-piperidin-1-ylpropan-2-yl] 4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-98e45f97eb5649e4a609cff9f20027c1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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