proline dl-form → [7-(Methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methanol

HRID 933612

Reaction equation

HRID 933612 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:13]1)[O:7][CH:8]([CH2:11][OH:12])[CH2:9][O:10]2.[CH3:14][S:15](=[O:16])[O-:17].[CH3:29][S:30]([CH3:31])=[O:32].[CH3:35][CH2:36][O:37][C:38]([CH3:39])=[O:40].[Cu:33][I:34].[Na+:18].[Na+:28].[OH-:27].[OH2:41].[OH:19][C:20]([CH:21]1[NH:22][CH2:23][CH2:24][CH2:25]1)=[O:26]>>[c:2]1([S:15]([CH3:14])(=[O:16])=[O:17])[cH:3][cH:4][c:5]2[c:6]([cH:13]1)[O:7][CH:8]([CH2:11][OH:12])[CH2:9][O:10]2

Participants

10

Reactant 9

HCID 614proline dl-formHCID 679Dimethyl SulfoxideHCID 923Sodium ion2×HCID 961HydroxideHCID 962WaterHCID 8857Ethyl AcetateHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 233965(7-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanolHCID 3870744Methanesulfinate

Product 1

HCID 66878354[7-(Methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methanol

Sources & evidence

ORD record
ord-ff5360088a9c4687b02dbfde8760ce36
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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