Hydrochloric Acid → Hydrochloric Acid

HRID 945682

Reaction equation

HRID 945682 reaction equation
[CH:37]([OH:38])([CH3:39])[CH3:40].[Cl:1][c:2]1[cH:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:15][CH2:16][n:17]3[n:18][cH:19][n:20][cH:21]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12.[Cl:22][c:23]1[cH:24][c:25]([F:30])[c:26]([NH2:27])[cH:28][cH:29]1.[ClH:31].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36]>>[ClH:1].[c:2]1([NH:27][c:26]2[c:25]([F:30])[cH:24][c:23]([Cl:22])[cH:29][cH:28]2)[cH:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:15][CH2:16][n:17]3[n:18][cH:19][n:20][cH:21]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12

Participants

7

Reactant 5

HCID 313Hydrochloric AcidHCID 3776IsopropanolHCID 6228DimethylformamideHCID 938984-Chloro-2-fluoroanilineHCID 226465544-Chloro-6-methoxy-7-(2-([1,2,4]-triazol-1-yl)ethoxy)quinoline

Product 2

HCID 313Hydrochloric AcidHCID 22646627N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[2-(1,2,4-triazol-1-yl)ethoxy]quinolin-4-amine

Sources & evidence

ORD record
ord-4861877a2daf4f7e8faae94a466137a0
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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