Tetrahydrofuran → 2-cyano-N-(2,4-dichloro-5-methoxyphenyl)acetamide

HRID 948084

Reaction equation

HRID 948084 reaction equation
[C:12](#[N:13])[CH2:14][C:15](=[O:16])[OH:17].[CH3:18][CH:19]([N:20]=[C:21]=[N:22][CH:23]([CH3:24])[CH3:25])[CH3:26].[Cl:1][c:2]1[c:3]([NH2:4])[cH:5][c:6]([O:10][CH3:11])[c:7]([Cl:9])[cH:8]1.[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1>>[Cl:1][c:2]1[c:3]([NH:4][C:15]([CH2:14][C:12]#[N:13])=[O:16])[cH:5][c:6]([O:10][CH3:11])[c:7]([Cl:9])[cH:8]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 9740Cyanoacetic acidHCID 12734DiisopropylcarbodiimideHCID 14766362,4-Dichloro-5-methoxyaniline

Product 1

HCID 160991782-cyano-N-(2,4-dichloro-5-methoxyphenyl)acetamide

Sources & evidence

ORD record
ord-7f888b74148e47c7b7645b2d19c23ac2
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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