1,2-Dichloroethane → Methyl 4-methyl-2-[[4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]pentanoate

HRID 952803

Reaction equation

HRID 952803 reaction equation
[CH2:18]([c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)[O:25][C:26](=[O:27])[NH:28][CH:29]([CH2:30][CH:31]([CH3:32])[CH3:33])[C:34](=[O:35])[OH:36].[CH2:37]([Cl:38])[CH2:39][Cl:40].[CH3:11][N:12]1[CH2:13][CH2:14][O:15][CH2:16][CH2:17]1.[CH3:42][O:43][C:44]([CH:45]([NH2:46])[CH2:47][CH:48]([CH3:49])[CH3:50])=[O:51].[Cl:52][CH2:53][Cl:54].[ClH:41].[OH:1][n:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7][cH:8]2)[n:9][n:10]1>>[CH2:18]([c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)[O:25][C:26](=[O:27])[NH:28][CH:29]([CH2:30][CH:31]([CH3:32])[CH3:33])[C:34](=[O:36])[NH:46][CH:45]([C:44]([O:43][CH3:42])=[O:51])[CH2:47][CH:48]([CH3:49])[CH3:50]

Participants

8

Reactant 7

HCID 111,2-DichloroethaneHCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 79724-MethylmorpholineHCID 757711-HydroxybenzotriazoleHCID 2466732-(((Benzyloxy)carbonyl)amino)-4-methylpentanoic acidHCID 410817Methyl DL-leucinate hydrochloride

Product 1

HCID 434890Methyl 4-methyl-2-[[4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]pentanoate

Sources & evidence

ORD record
ord-6d5b11e9270e4d4f876bd5b9bf1e0987
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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