Chloride → 3-Fluoropyridine-2-sulfonamide

HRID 960499

Reaction equation

HRID 960499 reaction equation
[C:19](=[O:20])([OH:21])[O-:22].[CH3:26][S:27](=[O:28])[CH3:29].[Cl-:25].[FH:12].[N:13]([O-:14])=[O:15].[N:17]#[N:18].[NH2:1][c:2]1[c:3]([S:8](=[O:9])(=[O:10])[NH2:11])[n:4][cH:5][cH:6][cH:7]1.[Na+:16].[Na+:23].[Na+:24]>>[c:2]1([F:12])[c:3]([S:8](=[O:9])(=[O:10])[NH2:11])[n:4][cH:5][cH:6][cH:7]1

Participants

9

Reactant 8

HCID 312ChlorideHCID 679Dimethyl SulfoxideHCID 769Bicarbonate IonHCID 923Sodium ion3×HCID 946NitriteHCID 947NitrogenHCID 14917Hydrofluoric AcidHCID 149437023-Aminopyridine-2-sulfonamide

Product 1

HCID 199579303-Fluoropyridine-2-sulfonamide

Sources & evidence

ORD record
ord-7ce7bb48f1744a20ad959c047523f90e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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