→ Ethyl 4-methyl-6-naphthalen-1-yl-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate

HRID 962314

Reaction equation

HRID 962314 reaction equation
C=CCNC(N)=O.CCO.CCOC(=O)CC(C)=O.O.O=Cc1cccc2ccccc12.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3]>>C=CCN1C(=O)NC(c2cccc3ccccc23)C(C(=O)OCC)=C1C

Participants

6

Reactant 0

No Reactant data yet.

Product 1

HCID 110273792Ethyl 4-methyl-6-naphthalen-1-yl-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylateYield 41%

Reagents, catalysts & solvents 5

HCID 702EthanolOther2×HCID 61951-NaphthaldehydeOtherHCID 8868Ethyl AcetoacetateOtherHCID 11181AllylureaOtherHCID 45075687Ytterbium(3+) trifluoromethanesulfonate--water (1/3/1)Other

Conditions

Temperature
120 °C

Workup

  1. waitNo procedure recorded
  2. additionNo procedure recorded
  3. waitNo procedure recorded
  4. filtrationKeep solid
  5. washNo procedure recorded
  6. dry in vacuumNo procedure recorded

Sources & evidence

ORD record
ord-f79687f5780940a9bbc2778ad8f13d9f
Source dataset
Microwave-assisted Biginelli Condensation Dataset
Original link
View source

Linked notes

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