Water → 4-(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]quinolin-7-yloxy)-N-[1-(phenylmethyl)-4-piperidinyl]butanamide

HRID 96568

Reaction equation

HRID 96568 reaction equation
[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[CH3:60][N:61]([CH3:62])[c:63]1[cH:64][cH:65][n:66][cH:67][cH:68]1.[CH3:70][N:71]([CH3:72])[CH:73]=[O:74].[NH2:22][CH:23]1[CH2:24][CH2:25][N:26]([CH2:29][c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[CH2:27][CH2:28]1.[O:1]=[c:2]1[nH:3][c:4]2[c:5]([n:6][c:7]3[cH:8][cH:9][c:10]([O:14][CH2:15][CH2:16][CH2:17][C:18](=[O:19])[OH:20])[cH:11][c:12]3[cH:13]2)[nH:21]1.[OH2:69].[c:43]1([P:44]([N:45]=[N+:46]=[N-:47])([c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)=[O:54])[cH:55][cH:56][cH:57][cH:58][cH:59]1>>[O:1]=[c:2]1[nH:3][c:4]2[c:5]([n:6][c:7]3[cH:8][cH:9][c:10]([O:14][CH2:15][CH2:16][CH2:17][C:18](=[O:20])[NH:22][CH:23]4[CH2:24][CH2:25][N:26]([CH2:29][c:30]5[cH:31][cH:32][cH:33][cH:34][cH:35]5)[CH2:27][CH2:28]4)[cH:11][c:12]3[cH:13]2)[nH:21]1

Participants

8

Reactant 7

HCID 962WaterHCID 6228DimethylformamideHCID 8471TriethylamineHCID 142844-(Dimethylamino)pyridineHCID 199401P,P-Diphenylphosphinic azideHCID 4158521-Benzyl-4-piperidylamineHCID 142809904-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-butyric acid

Product 1

HCID 150056464-(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]quinolin-7-yloxy)-N-[1-(phenylmethyl)-4-piperidinyl]butanamide

Sources & evidence

ORD record
ord-37fa81522e5b4205b930a0b0d138632a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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