Ammonium → Methyl 2-[2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]acetate
Reaction equation
[Br:20][CH2:21][C:22](=[O:23])[O:24][CH3:25].[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[Cl-:26].[F:1][c:2]1[cH:3][c:4]([C:9]2([CH3:18])[CH2:10][CH2:11][C:12]([CH3:16])([CH3:17])[C:13](=[O:15])[NH:14]2)[cH:5][c:6]([F:8])[cH:7]1.[KH:19].[NH4+:27]>>[F:1][c:2]1[cH:3][c:4]([C:9]2([CH3:18])[CH2:10][CH2:11][C:12]([CH3:16])([CH3:17])[C:13](=[O:15])[N:14]2[CH2:21][C:22](=[O:23])[O:24][CH3:25])[cH:5][c:6]([F:8])[cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-9fab38620a714f49820276e6d3a1a5f8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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