Acetic Acid → 4-Bromo-2-fluorobenzaldehyde

HRID 98032

Reaction equation

HRID 98032 reaction equation
[Br:12][c:13]1[c:14]([F:20])[cH:15][c:16]([Br:19])[cH:17][cH:18]1.[CH2:2]([Mg+:3])[CH2:4][CH2:5][CH3:6].[CH2:7]([Li:8])[CH2:9][CH2:10][CH3:11].[CH3:21][N:22]([CH:23]=[O:24])[CH3:25].[CH3:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36].[CH3:37][C:38](=[O:39])[OH:40].[CH3:41][c:42]1[cH:43][cH:44][cH:45][cH:46][cH:47]1.[Cl-:1].[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1>>[c:13]1([CH:23]=[O:24])[c:14]([F:20])[cH:15][c:16]([Br:19])[cH:17][cH:18]1

Participants

10

Reactant 9

HCID 176Acetic AcidHCID 312ChlorideHCID 1140TolueneHCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 8058HexaneHCID 1370041,4-Dibromo-2-fluorobenzeneHCID 178418339ButyllithiumHCID 178448190HCID 178448190, compound

Product 1

HCID 1435174-Bromo-2-fluorobenzaldehyde

Sources & evidence

ORD record
ord-c66ddab3fb0a43dd871d59661367943f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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