proline dl-form → 1-(2-Fluorophenyl)piperidine-4-carboxylic acid ethyl ester
Reaction equation
[C:20](=[O:21])([O-:22])[O-:23].[CH3:34][S:35](=[O:36])[CH3:37].[Cu:38]([I:39])[I:40].[F:1][c:2]1[c:3]([I:8])[cH:4][cH:5][cH:6][cH:7]1.[K+:24].[K+:25].[NH:9]1[CH2:10][CH2:11][CH:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[CH2:18][CH2:19]1.[OH2:41].[OH:26][C:27]([CH:28]1[NH:29][CH2:30][CH2:31][CH2:32]1)=[O:33]>>[F:1][c:2]1[c:3]([N:9]2[CH2:10][CH2:11][CH:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[CH2:18][CH2:19]2)[cH:4][cH:5][cH:6][cH:7]1Participants
9
Sources & evidence
- ORD record
- ord-9000e6ffd28e4110b716c4a0869a3676
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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