Pyridine → 2-methoxy-N,N-dimethyl-2-(2-pyridyl)thioacetamide
反応式
P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:2].[CH3:15][O:16][CH:17]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][N:24]=1)[C:18]([N:20]([CH3:22])[CH3:21])=O.N1C=CC=CC=1.[OH-].[Na+]>O>[CH3:15][O:16][CH:17]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][N:24]=1)[C:18]([N:20]([CH3:22])[CH3:21])=[S:2]参加物
6
実験手順
Phosphorus pentasulfide (4 g.) is added to 9.7 g. of 2-methoxy-N,N-dimethyl-2-(2-pyridyl)acetamide in 25 ml. of pyridine. The mixture is heated on a steam bath for 2 hours, then 250 ml. of water and 10 ml. of 5% aqueous sodium hydroxide solution are added. The mixture is extracted with chloroform and the extracts are dried and concentrated and the residue is recrystallized to give 2-methoxy-N,N-dimethyl-2-(2-pyridyl)-thioacetamide.
後処理
- temperatureThe mixture is heated on a steam bath for 2 hours
- extractionThe mixture is extracted with chloroform
- customthe extracts are dried
- concentrationconcentrated
- customthe residue is recrystallized
出典と根拠
- ORDレコード
- ord-4edc2293f27442a7ad821920b91a2c8e
- 出典データセット
- uspto-grants-1976_05
- 特許番号
- US03956494
反応ノート
読み込み中…