Water → HCID 70145705、化合物
反応式
[CH2:1]([OH:6])/[CH:2]=[CH:3]\[CH2:4][CH3:5].[H-].[Na+].Cl[C:10]1[C:14]([C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)=[N:13][S:12][N:11]=1.O>O1CCCC1>[CH2:1]([O:6][C:10]1[C:14]([C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)=[N:13][S:12][N:11]=1)/[CH:2]=[CH:3]\[CH2:4][CH3:5]参加物
6
実験手順
To a solution of cis-2-penten-1-ol (780 mg, 9 mmol) and sodium hydride (310 mg, 9 mmol) in dry tetrahydrofuran was added a solution of 3-(3-chloro-1,2,5-thiadiazol-4-yl)pyridine (590 mg, 3 mmol) in dry tetrahydrofuran. The reaction mixture was stirred at room temperature for 1 h. Water was added and the mixture was extracted with ether. The ether phase was dried and evaporated to give the title compound.
後処理
- extractionthe mixture was extracted with ether
- dry with materialThe ether phase was dried
- customevaporated
出典と根拠
- ORDレコード
- ord-ee240518c3a34f70958505b9f701bdf7
- 出典データセット
- uspto-grants-1996_08
- 特許番号
- US05545638
反応ノート
読み込み中…